Javed F, Al-Askar M, Qayyum F, Wang HL, Al-Hezaimi K.Oral Squamous Cell Carcinoma Arising Around Osseointegrated Dental Implants. Implant Dent. 2012 Aug;21(4):280-286.

PURPOSE:

This literature review investigates the occurrence of oral squamous cell carcinoma (OSCC) around osseointegrated dental implants (DI).

METHODS:

Databases were searched from 1989 up to and including November 2011. The eligibility criteria were as follows: (1) original studies, (2) clinical studies and case reports, (3) reference lists of the relevant original and review articles, (4) intervention: occurrence of OSSC around osseointegrated DI, and (5) articles published only in English language.

RESULTS:

Fourteen studies were included. In nine studies, the dental implant patients with diagnosed OSCC had previously been exposed to cancer. In five studies, the patients presented with a history of habitual tobacco smoking and alcohol consumption.

CONCLUSION:

OSCC is more likely to arise around osseointegrated DI in patients with a previous history of cancer. However, the role of other factors including tobacco and alcohol usage cannot be disregarded.